Keep track of Carefully (1)pentobarbital will lessen the extent or influence of exemestane by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of. For clients receiving exemestane which has a powerful CYP3A4 inducer the advisable dose of exemestane is 50 mg day-to-day after a meal.
Hypnotic doses of such barbiturates will not show up to noticeably impair uterine action through labor; whole anesthetic doses of barbiturates lower the pressure and frequency of uterine contractions; administration of sedative-hypnotic barbiturates on the mother during labor may possibly cause respiratory depression from the newborn
pentobarbital will lower the level or result of maraviroc by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
Watch Carefully (1)pentobarbital will lessen the extent or effect of linagliptin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on. Use of alternative remedies is strongly encouraged when linagliptin should be to be administered that has a CYP3A4 inducer
Insignificant (one)pentobarbital will decrease the extent or effect of paclitaxel protein bound by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unidentified.
Contraindicated (one)pentobarbital will minimize the extent or effect of lumacaftor/ivacaftor by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will reduce the extent or outcome of ziprasidone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Unfamiliar.
pentobarbital will lessen the extent or impact of pimavanserin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check. Avoid coadministration if possible. Check for diminished pimavanserin efficacy. An increase in pimavanserin dosage could possibly be essential.
fentanyl transmucosal and pentobarbital both boost sedation. Stay clear of or Use Alternate Drug. Restrict use to people for whom alternate therapy possibilities are inadequate
fentanyl transdermal and pentobarbital both equally enhance sedation. Keep away from or Use Alternate Drug. Restrict use to patients for whom alternate treatment method possibilities are inadequate
pentobarbital will lower the level or result of tinidazole by impacting check here hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
pentobarbital will reduce the extent or impact of diazepam buccal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on. Powerful or reasonable CYP3A4 inducers may possibly boost price of diazepam elimination; hence, efficacy of diazepam can be diminished.
Keep track of Intently (1)pentobarbital will minimize the level or influence of tadalafil by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will reduce the extent or influence of etoposide by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
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